Guidelines for Average-Risk Women

"Average risk" means you have no personal history of breast cancer, no known genetic mutations (BRCA1/BRCA2), no first-degree relatives with breast cancer, and no history of chest radiation therapy.

Organization When to Start How Often When to Stop
USPSTF (2024) Age 40 Every 2 years (biennial) Age 74 (insufficient evidence for 75+)
American Cancer Society Age 45 (optional from 40-44) Yearly ages 45-54; every 2 years at 55+ (or continue yearly) Continue as long as life expectancy β‰₯10 years
ACR / SBI Age 40 Yearly Continue as long as patient is in good health
ACOG Age 40 (no later than 50) Every 1-2 years (shared decision) Age 75+ based on health status and preferences
NCCN Age 40 Yearly Continue if life expectancy β‰₯10 years

Abbreviations: USPSTF = U.S. Preventive Services Task Force; ACR = American College of Radiology; SBI = Society of Breast Imaging; ACOG = American College of Obstetricians and Gynecologists; NCCN = National Comprehensive Cancer Network.

Why Do Guidelines Differ?

Different organizations weigh benefits and harms differently:

The USPSTF weighs avoiding false positives more heavily; radiology organizations prioritize catching every cancer. Neither approach is "wrong"β€”it's about personal values and risk tolerance.

πŸ’‘ Shared Decision-Making

Talk to your doctor about your personal risk factors, family history, and preferences. You can start screening earlier or later than guidelines suggest based on your individual situation.

Higher-Risk Women: Special Guidelines

If you have certain risk factors, you may need to start screening earlier and/or add MRI to your screening regimen.

Who Is Considered Higher Risk?

Screening Recommendations for High-Risk Women

Risk Factor When to Start Imaging Type
BRCA1/BRCA2 mutation Age 25-30 Annual MRI + annual mammogram
Prior chest radiation 8-10 years after radiation (but not before age 25) Annual MRI + annual mammogram
First-degree relative with breast cancer 10 years before relative's diagnosis age (but not before 30) Annual mammogram; consider MRI if lifetime risk β‰₯20%
Lifetime risk β‰₯20% Age 30 (or earlier based on risk model) Annual MRI + annual mammogram

⚠️ Know Your Risk

If you have a family history of breast or ovarian cancer, talk to your doctor about genetic counseling and risk assessment. Tools like the Tyrer-Cuzick model can estimate your lifetime risk and guide screening decisions.

What About Dense Breasts?

About 40-50% of women have dense breasts. Dense breast tissue can hide cancers on mammograms and is associated with slightly higher breast cancer risk.

For women with dense breasts, some organizations recommend considering supplemental screening with:

The FDA now requires mammography facilities to report breast density. If you have dense breasts, discuss supplemental screening options with your doctor.

Learn more about dense breasts β†’

When to Stop Screening

The decision to stop screening is personal and depends on:

The USPSTF says evidence is insufficient to recommend for or against screening women 75+. Other organizations say to continue as long as the patient is in good health with reasonable life expectancy.